I pretty much agree with DGrangeRx33 regarding Dejuan Blair. A couple of important additional notes regarding Blair though...
Blair is essentially unprecedentedly vertically challenged at the power forward position. Yes, guys his size have been able to succeed in the NBA. BUT, for the most part, said guys have been significantly athletically superior and more skilled than Blair. The closest comparisons for Blair are probably Millsap and Maxiell - BUT they have an advantage on Blair regarding their No Step Vertical Reach. Below is a link to modern NBA prospects sorted by this metric.
http://www.draftexpress.com/nba-pre-draft-measurements/?year=All&sort2=DESC&draft=0&pos=4&sort=9Unfortunately, Blair falls below what appears to be a true line representing a players potential to survive at the PF position. He can reach just over 11'. The 'line' he would need to reach is merely an inch or so away. If he could improve his verticality by even an inch or two, he'd have a great chance to be Millsap-like. The problem is that Blair has just dropped a bunch of weight and even with this new-found 'explosiveness', he doesn't reach the bare minimum for this metric. Sure, he could work his way to do so, but it's a question mark. Furthermore, it's likely that his earthboundedness results from one of two sources - his weight or his knees. Two more question marks.
Another huge factor regarding Blair is that his NCAA dominance was at a much heavier weight. Besides workouts, he hasn't tried out his new body in true 5 on 5 game play. Will he be as effective with his unique style of play at a significantly lower weight? (<- Question mark).
There are simply too many question marks to consider drafting Blair in the first half of the first round. Is it possible that he is a totally unique player that will succeed in the NBA? Sure. At the very least, he should be able to act as an enforcer-type. Perhaps his wide body will mask his lateral weakness so that it takes more movement to move past him (he'll be able to hold his position). And his girth might allow him to carve out enough space so that he can maneuver effectively enough to rebound and score. I think it's too much conjecture.
I prefer to go with a player whose metrics suggest he should be able to succeed (Earl Clark, by the way, is freaking awesome measurement-wise - just needs strength). I would sooner draft Blair to play for the Colts than the Pacers. At 300+ lbs., his feet are quick, and his solid height, low center of gravity, and massive wingspan are ideal for fighting on the line of scrimmage.
EDIT: If they still allowed prolific hand-checking, I would give Blair a much better shot at being able at least succeed defensively. His wing-span would really come into play, and he should really be able to keep opposing bigs away from the basket. Now days though, plenty of guys will just blow right past him and he has no chance at the block from behind.