
VS.

The season arrives after lockout-mania, an exciting free agency period, and a short sloppy preseason. The youth movement is on in Seattle, who saw an offseason of goodbyes to the old guard as Matt Hasselbeck, Lofa Tutupu, Lawyer Milloy, Sean Locklear, and several others were replaced by whipper snappers such as Kam Chancellor, James Carpenter, Tarvaris Jackson, Zack Miller, and Sidney Rice.
With Tom Cable on board the revamped line will emphasize a road grading ground attack in Search of Seattles first 1,000 yard rusher since Shawn Alexander, while trying to keep Jackson healthy enough to make it through the year as head stop-gap.
SF comes in with a rookie head coach, QB issues similar to Seattle's, a vicious group of linebackers, and Frank Gore. The Harbaugh vs Carroll saga continues as both teams fans tryout the phrase "suck for luck".
Injury update:

Seahawks-
Deon Butler (WR), Roy Lewis (CB), and Cameron Morrah (TE), John Carlson Gone forever (shoulder), Sidney Rice (WR) is looking doubtful with a nagging shoulder injury, and Robert Gallery (G) is looking doubtful with a sprained knee.
49ers-
Dashon Goldston (S) knee
Things to Watch:
1-Offensive line shuffle
In the absence of Gallery Carpenter will slide to left guard while the emerging Breno Giocomini takes his 6'7" nasty frame to the right tackle spot. This could allow Carpenter to maul and provide for a really powerful left side, or it could be more of the run for your life show starring Tarvaris Jackson.
2-Pre-snap defensive adjustments
David Hawthorne's brain will be on trial in the absence of Lofa Tatupu. Athletically, he should be a big upgrade, however, it will be interesting to watch his chess game as the full time starting middle linebacker.
3-Cornerbacks who look like linebackers
Browner will start. If the refs don't ride him for manhandling the 9er receivers he could be a giant upgrade to Kelly Jennings (sorry bout that)
4-The lesser entities in the middle of the D
Collin Cole is out, Branch is in with some quirky depth behind him. We can guess what kind of play Mebane and Bryant will bring, but the question mark is going to point at the mammoth Allan Branch when Gore comes running down hill.
5-Golden Momentum
Tate picked a good game to show why he was a 2nd round pick with upside. It will be interesting to see if that carries over and he's the hot target in the slot that can make a difference.
Predictions-
Seahawk youthiness will give SF the edge and in the end, both teams will be pining for a new QB.
SF wins 17-13