I don't know if it'd be possible without giving up CJ, but I could get behind DeRozan. And if it came down to it, I'd rather have DeRozan than CJ. The ways that I think he helps the Blazers especially are his A/TO ratio and his FT rate--two things that would VASTLY help the team. He's a career 83% FT shooter too, which helps. Additionally, he's played SF the past couple of years and done well in that role.
The Blazers offense would need a bit of tweaking with a player like him. The SF under Stotts all too often gets stuck in the corner and ends up as the 3rd or 4th pass outlet to a 3 pointer...that's part of why Aminu took so many of them. Now, unlike Aminu, DeRozan has a dribble drive game. But as any coach would say, you never want a driving player in the corner because the two sidelines act like two defenders. So, likely the SG and SF positions would have to switch actions under Stotts--with Lillard and DDR being the 2 up in the 2-3 sets...
CJ would straight up feast in that role you described above. He is asked to do far too much right now. Get him open looks and I suspect you get JJ type efficiency from him. His role should be off ball movement shooter, not a iso guy.
I wouldnt move CJ for DDR, that makes the team basically the same level of talent as we have now. I want to add him to the guard duo and allow CJ a new role, allow Dame some time off ball, alleviate the trapping issue, get easy buckets (Both drives and FT), etc. We have two years to make a run until we have to resign Nurkic and truly be in cap hell. If we could get DDR for those two years, it would be huge.