The New Orleans Saints are 0-2 for the fourth straight season and are just 1-11 in the month of September since the start of the 2014 season.
"It puts you in a little bit of a hole, but again we can't cry over spilled milk here," Drew Brees said. "We have to press on, and we've got to find a way to get a win."
The Saints' struggles early on come after they opened the 2013 season at 4-0.
New Orleans has trailed by double digits for the entire second half of both games so far.
"I'm not concerned," Brees said. "Listen, it's only a matter of time. I felt like there were some things that came together this week that weren't there last week, or that were better. It just hasn't been good enough yet."
The Saints will play the Carolina Panthers in Week 3.