The Seattle Seahawks will be without defensive lineman Jarran Reed for the first six games of the season.
Reed was suspended six games for a violation of the personal conduct policy for an incident from early 2017.
He appealed, but it was denied on Friday morning.
The 26-year-old is coming off a breakout campaign in 2018 in which he compiled 10.5 sacks and 50 tackles in 16 regular-season starts.
Via Kevin Patra/NFL