Lionel Messi exited Inter Miami\'s 4-0 win over Toronto FC in the 37th minute due to muscle fatigue.
Messi will miss Sunday\'s match against Orlando City so he could increase his chances of playing in next Wednesday\'s U.S. Open Cup final.
Wednesday\'s match was the first of six for Inter Miami in a span of 17 days.
Messi entered Wednesday having appeared in 11 matches for Miami, most of them in Leagues Cup and U.S. Open Cup competition.