Manchester City at Liverpool (Sunday, 8:37 AM EST): The winner of the Premier League will almost certainly be either Manchester City (66 percent) or Liverpool (24 percent) and they meet at Anfield just two days before the 25th anniversary of the Hillsborough tragedy. There's still more than a month remaining in the EPL season, so the title won't be decided on this day but a team collecting three points would clearly be in the driver's seat.
Liverpool has been the world's most dominant club since the start of 2014, scoring early and often behind Luis Suárez and Daniel Sturridge.
Manchester City beat Liverpool by a 2-1 result earlier in the season, but this is a a very different club and they've been able to hit an extra gear in their home matches.
City clearly has a stronger defense and a tie would be a far better result for Manuel Pellegrini than it would be for Brendan Rodgers due to their games at hand. Multiple goals are expected, however, due to the aggressive nature of the Liverpool counterattack.
Arsenal vs. Wigan Athletic (Saturday, 12:07 PM EST): Arsenal had EPL title hopes early in the season after a strong start against weak competition, but they have regressed with their dismal record against the other top-4 clubs and a heap of key injuries.
We don't know for certain if Arsène Wenger will remain at Arsenal next season and this is a key opportunity to win their first trophy in nine years.
Wigan is undefeated in their previous 12 FA Cup games, but Arsenal are clear favorites due to the depth of quality they still have available.