Sergio Agüero will be out up to seven weeks with knee ligament damage.
Agüergo suffered distension of the lateral ligament of his left knee, according to reports in his homeland.
Manchester City is relieved Agüero didn't suffer more damage to the knee, though full results will be revealed on Monday or Tuesday.
But Manuel Pellegrinit faces a problem at striker with with Stevan Jovetic, who would normally start instead of Agüero, a doubt because of a hamstring problem while Edin Dzeko is not 100% fit following a calf injury.