Juan Carlos Osorio has quit after three years as manager of Mexico.
Osorio, 56, had rejected offers from the Mexican Football Federation (FMF) to extend his contract.
He said: "In my own name and in that of my backroom staff, many thanks to everyone for this unique and unparalleled professional and life experience."
Mexico were knocked out of the World Cup in the last 16, losing 2-0 to Brazil.