Coronavirus/COVID-19

[K For Three]

Spoiler:

not meant in bad taste but thats reality now

This.

[itrsteve]

Damn, I picked up game tickets and airfare to fly up for the Apr 3rd game against Orlando.

Looking extra unlikely now.

Would have much preferred to spend that wasted money on TP at Costco

[Curmudgeon]

PS Understand that carefully designed & adequately powered, randomized, double blind, prospective Phase 3 clinical trials are required by the FDA to prove that a drug has appropriate efficacy & an acceptable safety profile. Random off the cuff use of 1 of these 3 drugs in a VERY ill CORVID 19 patient is reasonable in the absence of an approved anti-viral therapy, but proves nothing.

If the patient receiving the drug lives when he or she would otherwise have died, that proves something, yes? We are not looking for Campbell and Stanley purity here, are we?

[K For Three]

Damn, I picked up game tickets and airfare to fly up for the Apr 3rd game against Orlando.

Looking extra unlikely now.

Would have much preferred to spend that wasted money on TP at Costco

You should see the amount of toilet paper my sister bought off amazon a week ago. I am both proud and disgusted at the same time of her. She has tons of rolls stacked up in her living room.

My mother has enough tuna fish cans for a year. She even has a lot of medical masks my father picked up in January!!! (we aren't wearing masks though-still in rural Mass where risk is lower)

Me? I'm a hand sanitizer and cereal hoarder/rice cake whore all the way.

I love sanitizer. Managed to get a full box of it before it went out of stock!!!!!!

And clorox wipes. **** yeah! Can never have enough of those bad boys around. Love wiping everything down.

I will admit my family has often been a bit of the cautious type.

[exculpatory]

PS Understand that carefully designed & adequately powered, randomized, double blind, prospective Phase 3 clinical trials are required by the FDA to prove that a drug has appropriate efficacy & an acceptable safety profile. Random off the cuff use of 1 of these 3 drugs in a VERY ill CORVID 19 patient is reasonable in the absence of an approved anti-viral therapy, but proves nothing.

If the patient receiving the drug lives when he or she would otherwise have died, that proves something, yes? We are not looking for Campbell and Stanley purity here, are we?

Read what I wrote.
If the patient survives, great.
But it does not prove the drug was the reason.

[Slax]

PS Understand that carefully designed & adequately powered, randomized, double blind, prospective Phase 3 clinical trials are required by the FDA to prove that a drug has appropriate efficacy & an acceptable safety profile. Random off the cuff use of 1 of these 3 drugs in a VERY ill CORVID 19 patient is reasonable in the absence of an approved anti-viral therapy, but proves nothing.

If the patient receiving the drug lives when he or she would otherwise have died, that proves something, yes? We are not looking for Campbell and Stanley purity here, are we?

My grandmother nearly died from pneumonia a couple years ago. To our great fortune - and against the prognosis of her own doctors - she somehow survived. If she had been given anti-virals, maybe we would be attributing her survival to the treatment, instead of just standard hospital care and luck.

[Curmudgeon]

PS Understand that carefully designed & adequately powered, randomized, double blind, prospective Phase 3 clinical trials are required by the FDA to prove that a drug has appropriate efficacy & an acceptable safety profile. Random off the cuff use of 1 of these 3 drugs in a VERY ill CORVID 19 patient is reasonable in the absence of an approved anti-viral therapy, but proves nothing.

If the patient receiving the drug lives when he or she would otherwise have died, that proves something, yes? We are not looking for Campbell and Stanley purity here, are we?

Read what I wrote.

Yes, I agree with the bolded. But it's the new drugs that need to be tested asap. On people. Think Walter Reed.

[Slax]

The hospital my wife works in has their first COVID-19 case. Pretty scary! This is the first time I've felt like it's an imminent threat instead of an abstract one.

[K For Three]

The hospital my wife works in has their first COVID-19 case. Pretty scary! This is the first time I've felt like it's an imminent threat instead of an abstract one.

Not good news at all.

[exculpatory]

If the patient receiving the drug lives when he or she would otherwise have died, that proves something, yes? We are not looking for Campbell and Stanley purity here, are we?

Read what I wrote.

Yes, I agree with the bolded. But it's the new drugs that need to be tested asap. On people. Think Walter Reed.

Read the entirety of my earlier detailed note.
There ARE small trials underway & large trials about to start for the IV anti-viral I described above.

Copied & pasted just for you: REMDESIVIR

Gilead Sciences
Stage: Phase 3
“Gilead’s remdesivir, an intravenous treatment, has already been used to treat one infected patient in the U.S. and will soon be deployed in a pair of large, late-stage studies in Asia. Later this month, Gilead will recruit about 1,000 patients diagnosed with the coronavirus to determine whether multiple doses of remdesivir can reverse the infection. The primary goals are reducing fever and helping patients get out of the hospital within two weeks. The drug, which previously failed in a study on Ebola virus, is also being studied in smaller trials in China and the U.S.”

[CSL_1904]

Things are getting a bit out of control over here in Europe. This is really bad, the worst side of globalization. Still, it baffles me that authorities are not better prepared to deal with stuff like this and in many cases have reacted far too late and not with enough force to prevent the spreading.

Unfortunately I believe it's just a matter of days before this becomes a real issue in the US aswell. Good luck to you guys.

[Curmudgeon]

The drug, which previously failed in a study on Ebola virus, is also being studied in smaller trials in China and the U.S.”

Yes, and if that doesn't work, try something else.

[Parliament10]

Gov. Baker declares state of emergency as Massachusetts coronavirus cases more than double to 92

Watch on YouTube

Watch on YouTube

[aggerrard]

Things are getting a bit out of control over here in Europe. This is really bad, the worst side of globalization. Still, it baffles me that authorities are not better prepared to deal with stuff like this and in many cases have reacted far too late and not with enough force to prevent the spreading.

Unfortunately I believe it's just a matter of days before this becomes a real issue in the US aswell. Good luck to you guys.

Yeah, it's scary. It went south really quick. The situation in Italy and particularly Nothern Italy might be what other european countries can expect aswell. Lombardia was the 'epicenter' of the outbreak in Europa as far as i know, so that can play a role in that area being hit so hard - where the virus is more spreadout in other European countries so those countries have better tools to control the virus.

Just talking 'bout European countries here. Some countries needs to be more cautious or the entire Europe quickly finds themselves in a situation like the one in Italy. In Denmark the outbreak went from 0 to 100 in the matter of two days. From 10 infected last sunday to more than 250 yesterday (tuesday) - and i'm waiting for the new numbers today, i wouldn't be surprised if we reaches more than 500 in the next few days. A few days ago a plane landed in Copenhagen from Nothern Italy and 50 Italians just got off the plane and walked down to the metro into the city. No testing, nothing. Meanwhile the government have advised all danish people returning from Nothern Italy (among other areas) to stay 14 days in quarantine.

Another problem is those who doesn't respect the quarantine - and just goes out in the public anyway and possible infecting others who then infects others and so the circle goes.

And we still have does who just talks about this as some normal flu. I don't know about the protocol in all european countries, but in Denmark the advice is still - wash you hands and if you're coming home from a 'high-risk' country please take an voluntary 14 days quarantine. Ofc the government are trying its best to trace down every person being in contact with those infected and placing them in a 14-quarantine. But people really needs to take this threat serious and be very cautious in public areas. 85% might be cautious but if the last 15% isn't, there is no end to this.

[Andrew McCeltic]

Haven't been posting here much lately, but sad to see the progress of this thread.. It's still not-the-end-of-the-world, but the stories about overburdened hospitals in Italy are sobering - it's not just that there won't be enough beds for people with coronavirus infection, but the quality of care will decline across the board.. Social distancing as a preventive measure seems more and more advisable to slow community spread.. And I don't know what it means for businesses and their workers who depend on physical customer traffic..

Currently I have weeks of toilet paper and days of food, so I'll need to figure that one out.

[BillessuR6]

In Slovenia we have 36 cases as of today. For a small country of 2 million it is quite a lot. The problem is we are neighbouring Italy. State border was closed today, so that should help but I think it was too late. With the way this is spreading in Europe I wonder how bad it can actually get. I also expect I will be working from home in a week or two as the virus is bound to spread in the region where I live…

[Mr_Mojo_Risin]

The situation in the US and Boston is following an ominous trend. I hope you all stay safe and well.

[Froob]

The hospital my wife works in has their first COVID-19 case. Pretty scary! This is the first time I've felt like it's an imminent threat instead of an abstract one.

Where are you guys? We’re waiting any day now for it to hit Maine. I work at a hospital up here and we’ve been preparing for it. Fully expecting major chances very soon.

[Pacino62]

I was in Jersey on business. Literally touched nothing and kept 5-6 feet from all of the people I work with when visiting them. One of the lifestyle plaza/malls I had to visit were discussing screening people for cold symptoms prior to letting them in. Crazy what’s happening out there

[chrisab123]

I'm not a doctor so maybe I'm missing something but IMO It's a flu that is hyped by fear. This is pretty ridiculous. I'm not canceling any of my travel plans and neither should anyone else. Also if anyone is pointing to the St Patricks Day parade as an indication of the severity of this then that is insane. Marty Walsh has probably wanted to get rid of that yearly headache for a couple of years. This is a good excuse to do so. Look, just wash your hands and stop buying an abundance of toilet paper and water. Everyone that doesn't have a shot immune system will be fine.

That being said if someone is willing to pay me 100k to contract the virus I'm all in.