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Clyde_Style wrote:Clyde_Style wrote:
I assume there are other people getting treatment for covid there. Shouldn't even be allowed
Dexamethasone is a long-acting glucocorticoid with a half-life of 36 to 72 hours, and is 6 times more potent than prednisone. Prednisone is shorter acting, with a half-life of 18 to 36 hours.
HarthorneWingo wrote:Clyde_Style wrote:
Well, I have to believe that those who trust and listen to the advice of our public health experts will survive and those who don't won't. Survival of the fitest.
thebuzzardman wrote:So, I had to look up the difference between Prednisone and Dexamethasone, as I have some passing familiarity with Prednisone.
My son got it a few times for his asthma, which he grew out of, thank god.
My dad got it at least once for pneumonia, and I think twice - he got pneumonia I believe twice within 5-7 years
I got it once for a pretty good case of bronchitis.
Now, I know it wired the f*ck out of my son when he was little, but I didn't appreciate how much until I was given it years later. It's fairly potent. It's potent enough that they always ramp up and ramp down the dosage.
Anyway, I wanted to see if Prednisone and Dexamethasone were the same thing, as Prednisone is fairly strong, but gets used often enough in a kind of routine way.
I was surprised to see Dexamethasone is SIX times stronger and lasts twice as long.
That's a pretty serious, not f*cking around drug.Dexamethasone is a long-acting glucocorticoid with a half-life of 36 to 72 hours, and is 6 times more potent than prednisone. Prednisone is shorter acting, with a half-life of 18 to 36 hours.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2718595/#:~:text=Dexamethasone%20is%20a%20long%2Dacting,of%2018%20to%2036%20hours.
omerome wrote:White House lying liar aka resident's mouthpiece aka "press secretary" has tested positive for COVID-19.
Here's my shocked face:
https://thehill.com/homenews/administration/519632-mcenany-tests-positive-for-covid-19
Cookies4Life wrote:thebuzzardman wrote:So, I had to look up the difference between Prednisone and Dexamethasone, as I have some passing familiarity with Prednisone.
My son got it a few times for his asthma, which he grew out of, thank god.
My dad got it at least once for pneumonia, and I think twice - he got pneumonia I believe twice within 5-7 years
I got it once for a pretty good case of bronchitis.
Now, I know it wired the f*ck out of my son when he was little, but I didn't appreciate how much until I was given it years later. It's fairly potent. It's potent enough that they always ramp up and ramp down the dosage.
Anyway, I wanted to see if Prednisone and Dexamethasone were the same thing, as Prednisone is fairly strong, but gets used often enough in a kind of routine way.
I was surprised to see Dexamethasone is SIX times stronger and lasts twice as long.
That's a pretty serious, not f*cking around drug.Dexamethasone is a long-acting glucocorticoid with a half-life of 36 to 72 hours, and is 6 times more potent than prednisone. Prednisone is shorter acting, with a half-life of 18 to 36 hours.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2718595/#:~:text=Dexamethasone%20is%20a%20long%2Dacting,of%2018%20to%2036%20hours.
Sorry to hear about your son's issues and glad to hear he improved greatly. Prednisone or Methylprednisone is also a steroid and works in the same manner as dexamethasone. These are just powerful anti-inflammatory meds.
Basically when someone is having extreme wheezing from their asthma this is due to bronchoconstriction where the airways are actually narrowing which makes it so much harder for them to breathe. They add the steroid in combination with a medication that causes bronchodilation or widens the airways- these are Beta 2 agonists like albuterol. The steroids are used as adjuvant therapy (add on meds) to decrease the amount of inflammation around the bronchoconstriction.
The problem with all steroids are their ridiculous side effect profiles especially if patients are on it for more than 1-2 weeks. That would be considered chronic therapy and it has a HOST of issues including elevating one's glucose levels (hyperglycemia) elevating your lipids (hyperlipidemia,) it can cause Cushing like symptoms which including easy bruising and bleeding.
It's a very tough drug and whenever a patient is on it, especially for a lengthy period of time, it needs to be tapered off (discharged from the person) slowly or it can cause a host of effects. So doctors will decrease the dosages in a decremental type of response to wean them off the steroids.
Trump being on it can be one of 2 things- he either had severe symptoms that warranted him being on it or his doctors just decided to throw everything but the kitchen sink on their immediate medical management for him. I think it's more than likely the latter but at this stage who knows.
Doctors don't like speaking about patients that aren't under their care because they don't know the specifics about the reason for their admissions. Even if they do know, they're bound to a strict code of patient-doctor confidentiality so they normally won't disclose information to the public- even about POTUS- unless gaining verbal or written consent from him.
robillionaire wrote:I'm actually on prednisone right now for various issues. was up until 5am the other night for no reason. anyway they seem determined to uphold his strongman image as evidenced by showing him signing his name to blank papers so he will probably come out of the hospital later and quietly recover in the bunker away from the public eye
The Trump family’s private concern about Trump’s behavior could raise questions about his fitness for office. Trump has been prescribed drugs that medical experts say can seriously impair his cognitive function. Last night the New York Times reported that steroids, which Trump is reportedly taking, specifically dexamethasone, are known to “affect mood, causing euphoria or a general happiness.”
cgmw wrote:Whatever happens, I'm hoping this bout of POTUS Covid takes the wind out of the sails of the radical right who primarily identify with shows of strength and abhor perceived weakness. Trump's instinct to parade himself around is correct, but it's coming off as pathetic and just hurting his image.
If a public show of POTUS vulnerability drives down donations and voting numbers it could cause the landslide needed to avoid lengthy litigation and the predictable legal obfuscation Republicans would unleash if it's close.
People think it's madness now, but it's not far-fetched that we're about to have a sitting American president who lost the popular vote by tens of millions and was only elected by the electoral college because courts are stacked with right wing judges.
Anyway, I realize this isn't the politics thread. But I just read the NYT and WSJ today, and honestly this thread is much more informative and interesting.
