Team USA defeated Puerto Rico 104-83 to finish 3-0 in group play on Saturday.
Team USA clinched the top overall seed in the knockout rounds and will play Brazil in the quarterfinals.
Anthony Edwards lead the game with 26 points on 11-15 shooting. Joel Embiid, who did not play against South Sudan, added 15 points.
Jrue Holiday missed the game due to ankle soreness. Jayson Tatum took his place in the starting lineup.