Random Thoughts XIX

[HeatFanLifer]

1) A vaccine is not coming soon, it could be 1 year to 18 months away. Here’s an article on why a vaccine is probable though.

Spoiler:

https://www.city-journal.org/coronavirus-vaccine

2) Lockdown allows replenishment of resources and buys time. With that time, we can look at better treatments. That’s the goal of flattening the curve.

3) You have been drafted for the Hunger Games

[AirP.]

1) A vaccine is not coming soon, it could be 1 year to 18 months away. Here’s an article on why a vaccine is probable though.

Spoiler:

https://www.city-journal.org/coronavirus-vaccine

2) Lockdown allows replenishment of resources and buys time. With that time, we can look at better treatments. That’s the goal of flattening the curve.

3) You have been drafted for the Hunger Games

1. Sure a vaccine is on the way, but like you said, 12 months to 18 months which is why I said it wasn't coming anytime soon (12-18 months isn't soon for a killer virus) and right smack in the middle... cold season where it could get much uglier than it can during the hot summer months. A lockdown for say, a few months isn't going to get us to the vaccine so we have to live with it until then, we can't lockdown this country for very long.

2. Lockdowns allow replenishment of resources and buy time, sure but there are adverse non-health related effects that will grow the longer we're locked down and when the lockdown is done, COVID-19 is just going to start spreading again, will we just lockdown again? It's a terrible situation with no good answers because not locking down has adverse effects and so does locking down. Personally I could handle being locked in since I'm essential personnel and can telecommunicate 100% of the time and have been doing that for weeks now. My family has taken this situation seriously since January, didn't know if it would get out of control but with the ease of long-range travel and people being way less considerate of other people thought there was a chance of this happening. I remember SARS in the early 2000s and taking similar precautions than too.

3. I couldn't care less.

[HeatFanLifer]

Woooow.

[eddieheatfan]

1) A vaccine is not coming soon, it could be 1 year to 18 months away. Here’s an article on why a vaccine is probable though.

Spoiler:

https://www.city-journal.org/coronavirus-vaccine

2) Lockdown allows replenishment of resources and buys time. With that time, we can look at better treatments. That’s the goal of flattening the curve.

3) You have been drafted for the Hunger Games

i would be weary of any type of vaccine that is rushed to the market because there's no SAR'S,MERS and AIDS VACCINES yet because of reasons.one of those reasons is that viruses do mutate pretty often and because of that is difficult to make a permanent vaccine.

that's why if you get the flu shot,it will only serve for one season and that's not a guarantee either because like i said viruses mutate and you will get "defense" for last's year strain of it

also theY have been trying to make vaccines for SARS and MERS but each time their test subjects have died terrible from side effects.

so yeah a vaccine is less likely,what am hopeful its for a treatment that will allow you to deal with the symptoms of this disease while it runs it course

https://en.wikipedia.org/wiki/COVID-19_vaccine

Previous efforts to develop vaccines for viruses in the family Coronaviridae that affect humans have been aimed at severe acute respiratory syndrome coronavirus (SARS) and Middle East respiratory syndrome (MERS). Vaccines against SARS[5] and MERS[6] have been tested in non-human animal models. As of 2020, there is no cure or protective vaccine for SARS that has been shown to be both safe and effective in humans

.

It is possible vaccines in development will not be safe or effective.[41] One study found that between 2006 and 2015, the success rate of obtaining approval from Phase I to successful Phase III trials was 11.5% for vaccines ("biologics").[42]

[HeatFanLifer]

Spoiler:

1) A vaccine is not coming soon, it could be 1 year to 18 months away. Here’s an article on why a vaccine is probable though.

https://www.city-journal.org/coronavirus-vaccine

2) Lockdown allows replenishment of resources and buys time. With that time, we can look at better treatments. That’s the goal of flattening the curve.

3) You have been drafted for the Hunger Games

i would be weary of any type of vaccine that is rushed to the market because there's no SAR'S,MERS and AIDS VACCINES yet because of reasons.one of those reasons is that viruses do mutate pretty often and because of that is difficult to make a permanent vaccine.

that's why if you get the flu shot,it will only serve for one season and that's not a guarantee either because like i said viruses mutate and you will get "defense" for last's year strain of it

also theY have been trying to make vaccines for SARS and MERS but each time their test subjects have died terrible from side effects.

so yeah a vaccine is less likely,what am hopeful its for a treatment that will allow you to deal with the symptoms of this disease while it runs it course

https://en.wikipedia.org/wiki/COVID-19_vaccine

Previous efforts to develop vaccines for viruses in the family Coronaviridae that affect humans have been aimed at severe acute respiratory syndrome coronavirus (SARS) and Middle East respiratory syndrome (MERS). Vaccines against SARS[5] and MERS[6] have been tested in non-human animal models. As of 2020, there is no cure or protective vaccine for SARS that has been shown to be both safe and effective in humans

.

It is possible vaccines in development will not be safe or effective.[41] One study found that between 2006 and 2015, the success rate of obtaining approval from Phase I to successful Phase III trials was 11.5% for vaccines ("biologics").[42]

Per the article I linked:

The biopharmaceutical industry will be able to make a Covid-19 vaccine—probably a few of them—using various existing vaccine technologies. But many people worry that Covid-19 will mutate and evade our vaccines, as the flu virus does each season. Covid-19 is fundamentally different from flu viruses, though, in ways that will allow our first-generation vaccines to hold up well. To the extent that Covid does mutate, it’s likely to do so much more slowly than the flu virus does, buying us time to create new and improved vaccines.

There is a critical difference between coronaviruses and flu. The novel coronavirus genome is made of one long strand of genetic code. This makes it an “unsegmented” virus—like a set of instructions that fit on a single page. The flu virus has eight genomic segments, so its code fits on eight “pages.” That’s not common for viruses, and it gives the flu a special ability. Because the major parts of the flu virus are described on separate pages (segments) of its genome, when two different flu viruses infect the same cell, they can swap pages.

It’s also important to note that while there was not a vaccine found for SARS viruses as of yet, there was a ton of research done already that has pinpointed the protein spikes as the key for inducing immunity. Will it succeed, who knows? But there’s hope and years of research to back it up.

Also, this is a good interview with one of the volunteers for a new Coronavirus vaccine:

https://www.technologyreview.com/s/615425/moderna-coronavirus-vaccine-test-subject-interview/

[eddieheatfan]

Spoiler:

1) A vaccine is not coming soon, it could be 1 year to 18 months away. Here’s an article on why a vaccine is probable though.

https://www.city-journal.org/coronavirus-vaccine

2) Lockdown allows replenishment of resources and buys time. With that time, we can look at better treatments. That’s the goal of flattening the curve.

3) You have been drafted for the Hunger Games

i would be weary of any type of vaccine that is rushed to the market because there's no SAR'S,MERS and AIDS VACCINES yet because of reasons.one of those reasons is that viruses do mutate pretty often and because of that is difficult to make a permanent vaccine.

that's why if you get the flu shot,it will only serve for one season and that's not a guarantee either because like i said viruses mutate and you will get "defense" for last's year strain of it

also theY have been trying to make vaccines for SARS and MERS but each time their test subjects have died terrible from side effects.

so yeah a vaccine is less likely,what am hopeful its for a treatment that will allow you to deal with the symptoms of this disease while it runs it course

https://en.wikipedia.org/wiki/COVID-19_vaccine

Previous efforts to develop vaccines for viruses in the family Coronaviridae that affect humans have been aimed at severe acute respiratory syndrome coronavirus (SARS) and Middle East respiratory syndrome (MERS). Vaccines against SARS[5] and MERS[6] have been tested in non-human animal models. As of 2020, there is no cure or protective vaccine for SARS that has been shown to be both safe and effective in humans

.

It is possible vaccines in development will not be safe or effective.[41] One study found that between 2006 and 2015, the success rate of obtaining approval from Phase I to successful Phase III trials was 11.5% for vaccines ("biologics").[42]

Per the article I linked:

The biopharmaceutical industry will be able to make a Covid-19 vaccine—probably a few of them—using various existing vaccine technologies. But many people worry that Covid-19 will mutate and evade our vaccines, as the flu virus does each season. Covid-19 is fundamentally different from flu viruses, though, in ways that will allow our first-generation vaccines to hold up well. To the extent that Covid does mutate, it’s likely to do so much more slowly than the flu virus does, buying us time to create new and improved vaccines.

There is a critical difference between coronaviruses and flu. The novel coronavirus genome is made of one long strand of genetic code. This makes it an “unsegmented” virus—like a set of instructions that fit on a single page. The flu virus has eight genomic segments, so its code fits on eight “pages.” That’s not common for viruses, and it gives the flu a special ability. Because the major parts of the flu virus are described on separate pages (segments) of its genome, when two different flu viruses infect the same cell, they can swap pages.

It’s also important to note that while there was not a vaccine found for SARS viruses as of yet, there was a ton of research done already that has pinpointed the protein spikes as the key for inducing immunity. Will it succeed, who knows? But there’s hope and years of research to back it up.

Also, this is a good interview with one of the volunteers for a new Coronavirus vaccine:

https://www.technologyreview.com/s/615425/moderna-coronavirus-vaccine-test-subject-interview/

time will tell if we are going to have an effective and long lasting vaccine without serious side effects.like i said,i would rather have better treatments to relieve or eliminate symptoms thus allowing the patients to recover faster and to hospitals to not be overcrowded by patients.

there are a few anti malaria and anti viral aids medications that seems to be promising as for treatments for this illness.also there are antibiotics just as azithromycin and vitamin C injections that seems to also be a cooperative treatment for ailing people.

https://www.pmlive.com/pharma_news/clinical_trial_of_gileads_coronavirus_hopeful_remdesivir_begins_in_uk_1334307

this has been already used in asiatic countries such as thailand,south korea,japan and china with some success

[HeatFanLifer]

Spoiler:

i would be weary of any type of vaccine that is rushed to the market because there's no SAR'S,MERS and AIDS VACCINES yet because of reasons.one of those reasons is that viruses do mutate pretty often and because of that is difficult to make a permanent vaccine.

that's why if you get the flu shot,it will only serve for one season and that's not a guarantee either because like i said viruses mutate and you will get "defense" for last's year strain of it

also theY have been trying to make vaccines for SARS and MERS but each time their test subjects have died terrible from side effects.

so yeah a vaccine is less likely,what am hopeful its for a treatment that will allow you to deal with the symptoms of this disease while it runs it course

https://en.wikipedia.org/wiki/COVID-19_vaccine

.

Per the article I linked:

The biopharmaceutical industry will be able to make a Covid-19 vaccine—probably a few of them—using various existing vaccine technologies. But many people worry that Covid-19 will mutate and evade our vaccines, as the flu virus does each season. Covid-19 is fundamentally different from flu viruses, though, in ways that will allow our first-generation vaccines to hold up well. To the extent that Covid does mutate, it’s likely to do so much more slowly than the flu virus does, buying us time to create new and improved vaccines.

There is a critical difference between coronaviruses and flu. The novel coronavirus genome is made of one long strand of genetic code. This makes it an “unsegmented” virus—like a set of instructions that fit on a single page. The flu virus has eight genomic segments, so its code fits on eight “pages.” That’s not common for viruses, and it gives the flu a special ability. Because the major parts of the flu virus are described on separate pages (segments) of its genome, when two different flu viruses infect the same cell, they can swap pages.

It’s also important to note that while there was not a vaccine found for SARS viruses as of yet, there was a ton of research done already that has pinpointed the protein spikes as the key for inducing immunity. Will it succeed, who knows? But there’s hope and years of research to back it up.

Also, this is a good interview with one of the volunteers for a new Coronavirus vaccine:

https://www.technologyreview.com/s/615425/moderna-coronavirus-vaccine-test-subject-interview/

time will tell if we are going to have an effective and long lasting vaccine without serious side effects.like i said,i would rather have better treatments to relieve or eliminate symptoms thus allowing the patients to recover faster and to hospitals to not be overcrowded by patients.

there are a few anti malaria and anti viral aids medications that seems to be promising as for treatments for this illness.also there are antibiotics just as azithromycin and vitamin C injections that seems to also be a cooperative treatment for ailing people.

https://www.pmlive.com/pharma_news/clinical_trial_of_gileads_coronavirus_hopeful_remdesivir_begins_in_uk_1334307

this has been already used in asiatic countries such as thailand,south korea,japan and china with some success

Yeah the anti malarial drugs seem very promising from what I have read. Lots of great minds put at work in this fight looking at this from countless angles.

[Bishop45]

1) A vaccine is not coming soon, it could be 1 year to 18 months away. Here’s an article on why a vaccine is probable though.

Spoiler:

https://www.city-journal.org/coronavirus-vaccine

2) Lockdown allows replenishment of resources and buys time. With that time, we can look at better treatments. That’s the goal of flattening the curve.

3) You have been drafted for the Hunger Games

1. Sure a vaccine is on the way, but like you said, 12 months to 18 months which is why I said it wasn't coming anytime soon (12-18 months isn't soon for a killer virus) and right smack in the middle... cold season where it could get much uglier than it can during the hot summer months. A lockdown for say, a few months isn't going to get us to the vaccine so we have to live with it until then, we can't lockdown this country for very long.

2. Lockdowns allow replenishment of resources and buy time, sure but there are adverse non-health related effects that will grow the longer we're locked down and when the lockdown is done, COVID-19 is just going to start spreading again, will we just lockdown again? It's a terrible situation with no good answers because not locking down has adverse effects and so does locking down. Personally I could handle being locked in since I'm essential personnel and can telecommunicate 100% of the time and have been doing that for weeks now. My family has taken this situation seriously since January, didn't know if it would get out of control but with the ease of long-range travel and people being way less considerate of other people thought there was a chance of this happening. I remember SARS in the early 2000s and taking similar precautions than too.

3. I couldn't care less.

Economy's going to hurt real bad, and continue that way until risks dwindle and we have a better contingency plan than "aw well, ppl are gonna die"

Needs to be, at least, accurate nationwide testing available before non-essential businesses can stand on their own. Though I doubt any sense of normalcy until this passes/vaccine is curated

[AirP.]

Economy's going to hurt real bad, and continue that way until risks dwindle and we have a better contingency plan than "aw well, ppl are gonna die"

Needs to be, at least, accurate nationwide testing available before non-essential businesses can stand on their own. Though I doubt any sense of normalcy until this passes/vaccine is curated

Oh, there's not going to be any normalcy till like you said, this passes or a vaccine is curated but you can't just stop society like this for all that long(I'm good with a short term shutdown to let everything ramp up to handle this the best they can) and not see negatives happening outside of the virus. I was actually surprised and happy to see a postcard show up at my house with coronavirus guidelines from the White House/CDC, not everyone watches the news or utilizes the internet. I'm highly interested what the exit strategy is from the lockdowns because there has to be one if nothing else strongly urging people to be less disgusting overall and possibly wearing face masks out in public (which will really help slow down the spread in public from people who don't know they have the virus), not a law but a strong recommendation where local areas could decide themselves on making it more then a recommendation and of course some businesses could make it mandatory for workers and customers wear them once their readily available to everyone.

I don't really believe in shutting down society, I believe educating and adapting society. I highly doubt this will be the last time we deal with a virus like this in the next decade or 2.

[Bishop45]

Economy's going to hurt real bad, and continue that way until risks dwindle and we have a better contingency plan than "aw well, ppl are gonna die"

Needs to be, at least, accurate nationwide testing available before non-essential businesses can stand on their own. Though I doubt any sense of normalcy until this passes/vaccine is curated

Oh, there's not going to be any normalcy till like you said, this passes or a vaccine is curated but you can't just stop society like this for all that long(I'm good with a short term shutdown to let everything ramp up to handle this the best they can) and not see negatives happening outside of the virus. I was actually surprised and happy to see a postcard show up at my house with coronavirus guidelines from the White House/CDC, not everyone watches the news or utilizes the internet. I'm highly interested what the exit strategy is from the lockdowns because there has to be one if nothing else strongly urging people to be less disgusting overall and possibly wearing face masks out in public (which will really help slow down the spread in public from people who don't know they have the virus), not a law but a strong recommendation where local areas could decide themselves on making it more then a recommendation and of course some businesses could make it mandatory for workers and customers wear them once their readily available to everyone.

I don't really believe in shutting down society, I believe educating and adapting society. I highly doubt this will be the last time we deal with a virus like this in the next decade or 2.

We're in agreement, although I don't really think a whole step up from lockdown is truly available to us in the near future as adapting would take an even greater shake up from the social order than we're used to. Leadership, nationwide, don't seem ready or willing.

If we open up stadiums, classrooms, gyms- we'd need to do so at maybe a third of their capacities and administer temperature checks and free testing everywhere. Not to mention drastic changes to travel. We can't stay closed, but we need more than stay-at-home orders to persist, otherwise can't open

[AirP.]

Economy's going to hurt real bad, and continue that way until risks dwindle and we have a better contingency plan than "aw well, ppl are gonna die"

Needs to be, at least, accurate nationwide testing available before non-essential businesses can stand on their own. Though I doubt any sense of normalcy until this passes/vaccine is curated

Oh, there's not going to be any normalcy till like you said, this passes or a vaccine is curated but you can't just stop society like this for all that long(I'm good with a short term shutdown to let everything ramp up to handle this the best they can) and not see negatives happening outside of the virus. I was actually surprised and happy to see a postcard show up at my house with coronavirus guidelines from the White House/CDC, not everyone watches the news or utilizes the internet. I'm highly interested what the exit strategy is from the lockdowns because there has to be one if nothing else strongly urging people to be less disgusting overall and possibly wearing face masks out in public (which will really help slow down the spread in public from people who don't know they have the virus), not a law but a strong recommendation where local areas could decide themselves on making it more then a recommendation and of course some businesses could make it mandatory for workers and customers wear them once their readily available to everyone.

I don't really believe in shutting down society, I believe educating and adapting society. I highly doubt this will be the last time we deal with a virus like this in the next decade or 2.

We're in agreement, although I don't really think a whole step up from lockdown is truly available to us in the near future as adapting would take an even greater shake up from the social order than we're used to. Leadership, nationwide, don't seem ready or willing.

If we open up stadiums, classrooms, gyms- we'd need to do so at maybe a third of their capacities and administer temperature checks and free testing everywhere. Not to mention drastic changes to travel. We can't stay closed, but we need more than stay-at-home orders to persist, otherwise can't open

Even if bigger venues are open, it doesn't mean just as many people will go as before this virus, in fact I think sports businesses need to be prepared for their revenue to continue to be low once they start back up until this virus is handled. I just worry about the younger adults and children who won't be taking this serious, continue to have a lot of contact with others and just end up being carriers. Just look at how the beaches were packed for spring break, they just don't care... and that's all around the country. Hopefully some curfews are put in place, it would at least be some time each day where contact would be limited other then when most are sleeping.

[AirP.]

Read on Twitter

[QUIZ]

Read on Twitter

Khabib would've lost if OP made this thread earlier phew

goodboy

Spoiler:

Read on Twitter

[goodboy]

its so stupid, just postpone the damn event. No other sports are taking places, not sure why dana is so hell-bent with this.

But its so obvious Dana could've did something with his power/money to Fly out Khabib anywhere.

He did this because he knows this fight needs an audience, plain and simple.

This is a bad match-up for Tony though, he never faced a top 5 LWH. Its still a very exciting fight nonethless.

[HeatFanLifer]

Spoiler:

Economy's going to hurt real bad, and continue that way until risks dwindle and we have a better contingency plan than "aw well, ppl are gonna die"

Needs to be, at least, accurate nationwide testing available before non-essential businesses can stand on their own. Though I doubt any sense of normalcy until this passes/vaccine is curated

Oh, there's not going to be any normalcy till like you said, this passes or a vaccine is curated but you can't just stop society like this for all that long(I'm good with a short term shutdown to let everything ramp up to handle this the best they can) and not see negatives happening outside of the virus. I was actually surprised and happy to see a postcard show up at my house with coronavirus guidelines from the White House/CDC, not everyone watches the news or utilizes the internet. I'm highly interested what the exit strategy is from the lockdowns because there has to be one if nothing else strongly urging people to be less disgusting overall and possibly wearing face masks out in public (which will really help slow down the spread in public from people who don't know they have the virus), not a law but a strong recommendation where local areas could decide themselves on making it more then a recommendation and of course some businesses could make it mandatory for workers and customers wear them once their readily available to everyone.

I don't really believe in shutting down society, I believe educating and adapting society. I highly doubt this will be the last time we deal with a virus like this in the next decade or 2.

We're in agreement, although I don't really think a whole step up from lockdown is truly available to us in the near future as adapting would take an even greater shake up from the social order than we're used to. Leadership, nationwide, don't seem ready or willing.

If we open up stadiums, classrooms, gyms- we'd need to do so at maybe a third of their capacities and administer temperature checks and free testing everywhere. Not to mention drastic changes to travel. We can't stay closed, but we need more than stay-at-home orders to persist, otherwise can't open

ICN airport in South Korea has walk-thru test sites that all non-symptomatic international non-citizen arrivals from hot spots must go through. These would be great to have at many high frequent traffic areas. Whether there should be mandatory screen though, randomized mandatory screening, or just voluntary is a loaded policy issue though.

Watch on YouTube

[QUIZ]

its so stupid, just postpone the damn event. No other sports are taking places, not sure why dana is so hell-bent with this.

But its so obvious Dana could've did something with his power/money to Fly out Khabib anywhere.

He did this because he knows this fight needs an audience, plain and simple.

This is a bad match-up for Tony though, he never faced a top 5 LWH. Its still a very exciting fight nonethless.

With Ramadan coming up Khabib likely won’t be ready until at least September. Dana probably figured he could get it in now and then.

[goodboy]

its so stupid, just postpone the damn event. No other sports are taking places, not sure why dana is so hell-bent with this.

But its so obvious Dana could've did something with his power/money to Fly out Khabib anywhere.

He did this because he knows this fight needs an audience, plain and simple.

This is a bad match-up for Tony though, he never faced a top 5 LWH. Its still a very exciting fight nonethless.

With Ramadan coming up Khabib likely won’t be ready until at least September. Dana probably figured he could get it in now and then.

Who knows when the sports world will come back.

Interview with Bret, Khabib mentioned he would be ready by early as August. I think that should be fair enough given circumstance.

[SerialChiller]

Hey all! Hows everyone doing? Here in North Bay Ontario Canada weve got 7 known cases so far in a population of about 50,000. Everything shut down almost it feels like the apocalypse. I still try to live as normal as possible but this really is crazy! I waited all winter for the basketball courts to be free of snow and now that its nice they are closed with a $1,000 fine for anyone who trys to play apparently.

[HeatFanLifer]

Hey all! Hows everyone doing? Here in North Bay Ontario Canada weve got 7 known cases so far in a population of about 50,000. Everything shut down almost it feels like the apocalypse. I still try to live as normal as possible but this really is crazy! I waited all winter for the basketball courts to be free of snow and now that its nice they are closed with a $1,000 fine for anyone who trys to play apparently.

That $1,000 fine... oof. Stay safe, be well breh. Go Heat.

[Bishop45]

Watch on YouTube